deChronic fatigue is a symptom that affects millions of people and causes enormous strain in everyday life. Those who suffer from persistent exhaustion quickly realize that it is not “normal” tiredness after a short night of sleep, but a profound lack of energy that affects the body, mind, and soul.
More and more people report persistent fatigue that continues despite sleep and rest. Often, the diagnosis remains unclear for years—many affected individuals desperately search for an explanation for their symptoms and for effective treatment that goes beyond simple advice.
Causes of Chronic Fatigue
The causes of chronic fatigue are diverse. Sometimes there is a clear medical underlying condition, such as an underactive thyroid, Lyme disease, or the aftereffects of cancer. Long COVID has also emerged as a significant cause—many patients report extreme exhaustion and concentration problems that do not subside even months after the infection.
Psychological strain, ongoing stress, or burnout can also lead to profound exhaustion. Sleep problems or nutrient deficiencies often play a role as well. And sometimes, despite extensive examinations, the cause remains unclear, which is particularly frustrating for those affected.
Diagnosis – the First Step Toward Clarity
Since chronic fatigue can have many possible causes, thorough diagnostics are essential. In addition to a detailed medical history, this includes blood tests that assess immune status, hormonal factors, inflammatory markers, and nutrient levels. Organ function and cardiovascular parameters are also frequently examined. Only when the causes are understood can targeted treatment begin.
Nutrient Deficiency as an Underestimated Cause
Not uncommonly, chronic fatigue is caused by a nutrient deficiency. Iron deficiency, for example, can lead to anemia; vitamin D deficiency impairs the immune system and mood, while a lack of magnesium or B vitamins weakens energy production in the cells. The mitochondria—the power plants of our cells—can also no longer function optimally when deficiencies persist over time.
This is where targeted infusion therapies come into play, supplying the body with essential micronutrients. At VitaSangius, we particularly recommend the spermidine infusion and the glutathione infusion.
- Spermidine activates the body’s own autophagy, the natural process of cellular cleanup. Through this process, damaged cellular components are broken down, cell health is improved, and energy production is supported in the long term. Especially in cases of fatigue and Long COVID, spermidine can help strengthen cellular resilience and restore vitality.
- Glutathion ist eines der wichtigsten körpereigenen Antioxidantien. Es schützt die Zellen vor oxidativem Stress, unterstützt die Entgiftung und fördert das Immunsystem. Eine Glutathion-Infusion kann bei chronischer Müdigkeit helfen, den Körper zu entlasten und das Energieniveau spürbar zu verbessern.
These infusions are part of our holistic approach and are individually tailored to the needs of our patients.
When Young, Active People Are Affected
It is particularly striking that many young people who were previously athletic, high-performing, and full of energy also report chronic fatigue. They experience a sudden decline in their resilience—simple everyday activities become a challenge. Precisely because they were accustomed to being active and strong, they often perceive this loss of vitality as deeply painful and existential.
It is not uncommon for them to encounter limitations even with their doctors: standard examinations provide no answers, and treatments fail to help. Many feel left alone—and begin searching for specialized approaches that go beyond conventional care.
Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS)
A specific form of chronic fatigue is Chronic Fatigue Syndrome (ME/CFS). This condition is characterized by severe, persistent exhaustion that is not relieved by rest. Even minimal physical or mental exertion can significantly worsen symptoms—a phenomenon known as post-exertional malaise (PEM).
The treatment of ME/CFS is complex. The primary focus is on identifying the underlying causes as clearly as possible. Since this is often not definitively achievable, therapies concentrate on symptom relief. This includes pain and sleep medications and, in some cases, antidepressants. A central role is played by so-called pacing—the conscious management and distribution of one’s own energy to avoid overexertion. Psychotherapeutic support and self-help groups can also provide important assistance in coping more effectively with the condition.
At VitaSangius, we complement these approaches with innovative procedures such as blood purification (double-filtration plasmapheresis, hemoperfusion) and infusion therapies that can help relieve the immune system and promote cellular health. Especially for patients with severe fatigue or ME/CFS, these methods can open up new perspectives. Further information can be found on our page about Long COVID and fatigue therapy at VitaSangius.
Long COVID and Chronic Fatigue
One area in which new perspectives have emerged is the treatment of Long COVID. At VitaSangius, we use blood purification procedures such as double-filtration plasmapheresis (DFPP) and hemoperfusion. These therapies can remove disease-causing proteins and inflammatory mediators from the blood, thereby relieving the immune system. Many patients report a significant improvement in their symptoms after treatment, along with increased energy and a regained sense of quality of life.
Such procedures can also have a supportive effect in cases of late-stage Lyme disease (see also therapy for Lyme disease), autoimmune disorders, or chronic inflammation. When combined with infusion therapies such as spermidine and glutathione, a sustainable treatment concept emerges that focuses on cellular regeneration, detoxification, and strengthening the immune system.
Coaching and psychological support
In addition to medical treatments, psychological support also plays an important role. Many patients feel burdened by their exhaustion not only physically but also emotionally. Uncertainty, anxiety, and the feeling of no longer being capable or productive further intensify the pressure.
At VitaSangius, we therefore also offer coaching and psychological support (learn more). This service helps patients develop new strategies for coping with the illness, reduce stress, and strengthen personal resources. In this way, a holistic approach is created that addresses both body and mind equally.
Fatigue as a Message
As much as chronic fatigue is a medical challenge, it can also be understood as a message. Fatigue forces us to pause; it draws attention to imbalances that we often ignore in everyday life. In a world geared toward speed, efficiency, and constant performance, exhaustion reveals our limits—and reminds us that health and balance cannot be taken for granted.
Therapies such as blood purification or infusion treatments can help address the biological causes. However, the true challenge remains bringing body and mind back into harmony and restoring a new sense of balance to one’s life.
Conclusion: Paths Back to Energy
Chronic fatigue is a complex phenomenon that must be taken seriously. Whether caused by Long COVID, ME/CFS, Lyme disease, burnout, or nutrient deficiencies—the causes may differ, but the experience of exhaustion is universal.
At VitaSangius, we combine medical precision with a holistic view of the individual. Through blood purification procedures, targeted infusion therapies with spermidine or glutathione, individualized coaching services, and comprehensive diagnostics, we support our patients on their journey out of exhaustion—toward renewed energy, vitality, and quality of life.
If you are also struggling with chronic fatigue, we warmly invite you to a no-obligation consultation. Together, we will discuss your personal situation and possible therapeutic approaches—so that you can find your way back to greater strength and quality of life.
